Unusual Presentations of Primary and Metastatic Adenoid Cystic Carcinoma Involving the Skin
Autor: | Phyu P. Aung, Victor G. Prieto, Katrina Collins |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Right shin Adenoid cystic carcinoma medicine.medical_treatment Lumpectomy Cutaneous lesion Nodule (medicine) Dermatology General Medicine medicine.disease behavioral disciplines and activities Pathology and Forensic Medicine stomatognathic diseases 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Biopsy Medicine Radiology medicine.symptom Presentation (obstetrics) business Mastectomy |
Zdroj: | The American Journal of Dermatopathology. 42:967-971 |
ISSN: | 0193-1091 |
Popis: | Adenoid cystic carcinoma (ACC) is most commonly seen in the salivary glands but may occur at other sites. Primary or metastatic involvement of the skin is unusual. We report 2 cases of ACC with unusual presentation. In the first case, a 55-year-old woman presented with a cutaneous lesion on the right shin, and final pathology showed ACC. An extracutaneous origin was excluded by clinical and imaging studies. In the second case, a 49-year-old woman presented with a nodule on the breast, and biopsy confirmed high-grade ACC (>30% solid areas). She underwent lumpectomy and subsequent mastectomy after recurrence. Sixteen months after the initial diagnosis of ACC of the breast, distant metastases at multiple sites, including the skin, were identified. This report will increase awareness of these rare presentations of cutaneous ACC and allow correct diagnosis and appropriate management of such cases. |
Databáze: | OpenAIRE |
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