| Popis: |
Purpose: This study evaluated the differences in treatment outcomes between misoprostol and surgical evacuation in the management of incomplete abortion. Methods: This retrospective cohort study compared patients with clinical diagnosis of incomplete abortion who underwent surgical or pharmacological (misoprostol) intervention, between the years 2014–2017. Demographics, sonographic results, treatment follow-up, and post-intervention data on retained products of conception were retrieved. A comparison was made between women with incomplete abortion who underwent surgical versus pharmacological intervention. Results: Among 589 spontaneous abortions, 198 were included in the study, of which 123 (62.1%) underwent surgical evacuation, and 75 (37.9%) pharmacological intervention with misoprostol. Baseline characteristics were similar between groups. During 130.8 ±91.7 days of follow-up, no patient who underwent surgical evacuation had retained products of conception or needed surgical hysteroscopy. Four cases (5.3%) in the misoprostol group had retained products of conception and needed hysteroscopy (p=0.02). Patients who underwent surgical evacuation had higher haemoglobin levels during follow-up (12.1 mg/dl vs. 11.7 mg/dl, p=0.05). No differences between groups in post-treatment pregnancy rates. Conclusion: Long-term follow-up after incomplete abortion showed that hemodynamically stable patients treated with misoprostol achieved the desired results in 95% of cases without any clinical changes in haemoglobin level or pregnancy interval. |
