Reentrainment in Golden Hamsters: Effect of Melatonin, Age and Neonatal Clomipramine Treatment
| Autor: | Paola C. Yannielli, Diego A. Golombek, Daniel P. Cardinali |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
photoperiodism
endocrine system Clomipramine medicine.medical_specialty Physiology Phase advance business.industry Dark cycle Pineal hormone Melatonin Endocrinology Physiology (medical) Internal medicine medicine Antidepressant Serotonin business Ecology Evolution Behavior and Systematics medicine.drug |
| Zdroj: | Biological Rhythm Research. 29:501-509 |
| ISSN: | 1744-4179 0929-1016 |
| Popis: | Golden hamsters (young: 3 month-old; old: more than 12 month-old; or neonatally treated with clomipramine – a serotonin/noradrenaline re-uptake inhibitor antidepressant) were initially entrained to a 14:10 light:dark cycle, and their reentrainment rate after a 6 h phase advance in the photoperiod was determined. Animals took between 6 and 9 days to reentrain. Melatonin (1 mg/kg, i.p.) accelerated reentrainment to the LD cycle in all groups, except for the clomipramine-treated hamsters. These results support an important accelerating effect of the pineal hormone melatonin on resynchronization, no longer observed in clomipramine-treated hamsters. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|