Rethinking Second-Line Therapy for Overactive Bladder to Improve Patient Access to Treatment Options
| Autor: | Evelyn Hall, Shailja Mehta, Olivia O Cardenas-Trowers, Alaina T. Bennett, Nancy E Ringel, Kerac N Falk, Kimia Menhaji, Hayley C. Barnes, Christina Escobar, Laura Tellechea, Olivia H. Chang, Sarah E S Jeney, Oluwateniola Brown, Elisabeth C. Sappenfield |
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| Rok vydání: | 2021 |
| Předmět: |
Chronic condition
medicine.medical_specialty 030219 obstetrics & reproductive medicine Side effect business.industry MEDLINE Obstetrics and Gynecology urologic and male genital diseases medicine.disease humanities female genital diseases and pregnancy complications 03 medical and health sciences Patient safety 0302 clinical medicine Quality of life (healthcare) Overactive bladder Health care medicine Dementia 030212 general & internal medicine business Intensive care medicine |
| Zdroj: | Obstetrics & Gynecology. 137:454-460 |
| ISSN: | 0029-7844 |
| Popis: | Idiopathic overactive bladder (OAB) is a chronic condition that negatively affects quality of life, and oral medications are an important component of the OAB treatment algorithm. Recent literature has shown that anticholinergics, the most commonly prescribed oral medication for the treatment of OAB, are associated with cognitive side effects including dementia. β3-adrenoceptor agonists, the only alternative oral treatment for OAB, are similar in efficacy to anticholinergics with a more favorable side effect profile without the same cognitive effects. However, there are marked cost variations and barriers to access for OAB medications, resulting in expensive copays and medication trial requirements that ultimately limit access to β3-adrenoceptor agonists and more advanced procedural therapies. This contributes to and perpetuates health care inequality by burdening the patients with the least resources with a greater risk of dementia. When prescribing these medications, health care professionals are caught in a delicate balancing act between cost and patient safety. Through multilevel collaboration, we can help disrupt health care inequalities and provide better care for patients with OAB. |
| Databáze: | OpenAIRE |
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