Impact of Dietary Intervention on Selected Biochemical Indices of Inflammation and Oxidative Stress in Nigerians with Metabolic Syndrome: A Pilot Study

Autor: O E Oyewole, M. O. Ebesunun, Adesoji Adedipe Fasanmade, J. A. Olaniyi, Unyime Aniekpon Fabian, Omolara Olutosin Popoola, Olufunke Olayemi Hassan, Jane Roli Adebusuyi, Sheu Kadiri Rahamon, E. O. Agbedana, Kehinde Adigun, K. S. Akinlade, Wemimo Okunbolade, Mayowa O. Owolabi, Olatunbosun Ganiyu Arinola, Mabel Ayebatonyo Charles-Davies
Rok vydání: 2014
Předmět:
Zdroj: European Journal of Nutrition & Food Safety. 4:137-149
ISSN: 2347-5641
DOI: 10.9734/ejnfs/2014/6604
Popis: Aim: This study assessed the impact of dietary modification on cardiometabolic, inflammatory and oxidative stress indices in Nigerians with metabolic syndrome (MS). Subjects and Methods: Sixty participants with MS were selected using the International Diabetes Federation criteria from a cohort participating in “Risk Assessment of Type 2 diabetes mellitus and Dementia in Nigerians with Metabolic Syndrome” study. The subjects were seen by a Dietitian and the approximate percentages of total calories from total protein, total fat, polyunsaturated fat, and carbohydrate were calculated from dietary history and pegged at 20%, 30%, 14% and 50% respectively. To ensure compliance, each participant was seen monthly (for 6 months) by the Dietitian. Glucose and lipid profile were determined using enzymatic methods. Serum activities of superoxide dismutase (SOD), catalase (CAT), Myeloperoxidase (MPO) and levels of nitric oxide (NO), malondialdehyde (MDA), hydrogen peroxide (H
Databáze: OpenAIRE