Biotin and fluorescein labeling of biomolecules by active esters of 1-phenylpyrazolin-5-ones

Autor:	Malcolm Pluskal, Shelagh Casey, Jonathan N. Kremsky, Steven A. Kates, Heather Perry-O'Keefe, Nanda D. Sinha
Rok vydání:	1996
Předmět:	chemistry.chemical_classification Oligonucleotide Biomolecule Organic Chemistry Peptide Biochemistry chemistry.chemical_compound chemistry Biotin Drug Discovery Organic chemistry Reactivity (chemistry) Carboxylate Fluorescein
Zdroj:	Tetrahedron Letters. 37:4313-4316
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00833-7
Popis:	The synthesis of 1-phenylpyrazolin-5-one carboxylate esters of biotin and fluorescein and their specific reactivity with amines under mild conditions to label various synthetic biopolymers such as oligonucleotides, peptides and PNA's is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d1efd180af4f8a171498c37f053c5e47 https://doi.org/10.1016/0040-4039(96)00833-7 Zobrazit plný text záznamu Full Text from ScienceDirect