Long-term follow-up of half-fluence photodynamic therapy in acute central serous chorioretinopathy
| Autor: | Eva Smretschnig, Jutta Gamper, Stefan Hagen, Ilse Krebs, Susanne Binder, Siamak Ansari-Shahrezaei |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
genetic structures medicine.diagnostic_test Long term follow up business.industry medicine.medical_treatment Photodynamic therapy Diabetic retinopathy medicine.disease Fluorescein angiography Verteporfin eye diseases 03 medical and health sciences Ophthalmology Serous fluid 0302 clinical medicine Quality of life Acute central serous chorioretinopathy 030221 ophthalmology & optometry Medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Spektrum der Augenheilkunde. 32:215-222 |
| ISSN: | 1613-7523 0930-4282 |
| DOI: | 10.1007/s00717-018-0412-y |
| Popis: | To evaluate the long-term results of indocyanine green angiography(ICGA)-guided verteporfin (Visudyne®, Novartis, Basel, Switzerland) photodynamic therapy (PDT) with half-fluence rate in the treatment of acute symptomatic central serous chorioretinopathy (CSC). A retrospective review was performed of 12 patients with acute symptomatic CSC verified by spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA), treated with ICGA-guided verteporfin (6 mg/m2)-PDT with half-fluence rate (25 J/cm2). The vision-related quality of life (VR QOL) 25-Item National Eye Institute Visual Function Questionnaire (VFQ-25) was completed by all patients and 82 controls. Best corrected visual acuity (BCVA) at baseline was 77.5 (±10; n = 12) according to the Early Treatment Diabetic Retinopathy Study (EDTRS) letter score and changed to 89 letters (±9.9; p = 0.0003) at long-term follow-up (83.8 ± 4.8 months after PDT). Baseline contrast sensitivity (CS) was 29.5 ± 4.5 Pelli–Robson letters and increased to 34.5 ± 4.5 letters at long term (p |
| Databáze: | OpenAIRE |
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