Mitochondria-targeted ratiometric fluorescent probes for micropolarity and microviscosity and their applications
| Autor: | Jingjing Cui, Weibing Zhang, Rui Huang, Junhong Qian, Yuhua Yao, Cong Chen |
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| Rok vydání: | 2019 |
| Předmět: |
Polarity (physics)
Chemistry 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Fluorescence 0104 chemical sciences Microviscosity Solvent Viscosity Wavelength Solvent polarity Biophysics 0210 nano-technology Mitochondria targeted |
| Zdroj: | Chinese Chemical Letters. 30:1071-1074 |
| ISSN: | 1001-8417 |
| Popis: | Two fluorescent “off-on” probes YYH1 and YYH2 were used for the detection of mitochondrial polarity and viscosity. Both probes have two emission bands: The peak of shorter wavelength was sensitive to the polarity, while that in longer wavelength region was sensitive to the viscosity, which enables us to detect medium polarity and viscosity simultaneously. The lg(Ishort/Ilong) of YYH1 exhibited linear relationship to the solvent polarity, while that of YYH2 was closely related to the solvent viscosity. Furthermore, both probes showed potential in bioimaging mitochondrial polarity or viscosity in living cells. |
| Databáze: | OpenAIRE |
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