Rate enhancement by water in a TiCl4-mediated stereoselective vinylogous Mukaiyama aldol reaction

Autor:	Makoto Yamaoka, Susumu Kobayashi, Atsuo Nakazaki
Rok vydání:	2010
Předmět:	Silylation Aldol reaction Chemistry Organic Chemistry Drug Discovery Organic chemistry Stereoselectivity Biochemistry Lewis acid catalysis
Zdroj:	Tetrahedron Letters. 51:287-289
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2009.10.140
Popis:	A remarkable enhancement in the rate of a TiCl4-mediated stereoselective vinylogous Mukaiyama aldol reaction (VMAR) using vinylketene silyl N,O-acetal 1 was observed in the presence of water.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d1c3dd053571064642d20868cc3baf95 https://doi.org/10.1016/j.tetlet.2009.10.140 Zobrazit plný text záznamu Full Text from ScienceDirect