Atrial electrophysiologic abnormalities in patients with wolff-parkinson-white syndrome but without paroxysmal atrial fibrillation

Autor: Hisanori Shinohara, Teru Nada, Koichi Sakabe, Tetsuzo Wakatsuki, Nobuo Fukuda, Akiyoshi Nishikado, Takashi Oki, Yoshiyuki Tamura
Rok vydání: 2004
Předmět:
Zdroj: Clinical Cardiology. 27:396-400
ISSN: 0160-9289
DOI: 10.1002/clc.4960270706
Popis: Background: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff-Parkinson-White (WPW) syndrome. Hypothesis: The purpose of this study was to analyze the atrial electrophysiologic abnormalities and vulnerability to develop atrial fibrillation (AF) in patients with WPW syndrome but with no previous history of PAF. Methods: We investigated atrial electrophysiologic abnormalities and vulnerability to AF in patients with WPW syndrome but without PAF. An electrophysiologic study was performed in 28 patients with WPW syndrome, 23 with atrioventricular nodal reentrant tachycardia (AVNRT) and 25 with other arrhythmias (control), all of whom had no history of PAF. The following atrial excitability parameters were assessed: effective refractory period (ERP), spontaneous or paced (A1) and extrastimulated (A2) atrial electrogram widths, percent maximum atrial fragmentation (%MAF; A2/A1 × 100), wavelength index (WLI; ERP/A2), and inducibility of AF. Results: The ERP tended to be shorter in patients with WPW syndrome and in those with AVNRT than in the control group. The %MAF increased (154 ± 33 vs. 137 ± 23%, p < 0.05) and WLI decreased (2.7 ±0.8 vs. 3.4 ± 1.0, p
Databáze: OpenAIRE