Evaluation the Effect of 50 g Glucose Tolerance Test on Oxidative Stress and Interleukin-8 Parameters in Prediabetic Pregnancy

Autor: Zeliha Cansel ÖZMEN, Cuma MERTOĞLU, Leyla AYDOĞAN, Mehmet Can NACAR, Köksal DEVECİ, Muzaffer KATAR, Zeki ÖZSOY
Rok vydání: 2022
Předmět:
Zdroj: Harran Üniversitesi Tıp Fakültesi Dergisi. :510-514
ISSN: 1304-9623
DOI: 10.35440/hutfd.1082328
Popis: Background: The aim of this study is to evaluate the effect of 50 g oral glucose tolerance test (OGTT) on oxidative stress and interleukin-8 (IL-8) parameters in prediabetic pregnant women. Materials and Methods: Fasting and 1 hour blood samples were collected from 79 pregnant women who were administered 50 gr OGTT. Patients with a 1 hour blood glucose level of 140–200 mg/dl were considered as the prediabetic group. Thereafter, routine biochemical parameters and the levels of superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA) and interleukin-8 (IL-8) parameters were measured from the serum samples taken during fasting and at 1 hour. Results: The serum GPx and SOD levels of the prediabetic group were remarkably lower than that of the control group (p
Databáze: OpenAIRE