Correlation Between Parathyroid Hormone Levels with Urinary Magnesium Excretion in Patients with Non-Dialysis Dependent Chronic Kidney Disease

Autor: Rayanna Cadilhe de Oliveira Costa, Alessandra Costa de Sales Muniz, Natalino Salgado Filho, Alcione Miranda dos Santos, Denizar Vianna Araújo, Dyego José de Araújo Brito, Raimunda Sheyla Carneiro Dias, Carla Déa Trindade Barbosa, Joyce Santos Lages, Mario Bernardo-Filho, Andrea Martins Melo Fontenele, Elisângela Milhomem Dos Santos, Ana Karina Teixeira da Cunha França, Elane Viana Hortegal Furtado, Maria Célia Cruz Diniz, Elton Jonh Freitas Santos, Érika Cristina Ribeiro de Lima Carneiro
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Nephrology and Renovascular Disease. 13:341-348
ISSN: 1178-7058
Popis: Background Disorders of mineral metabolism occur in most patients with chronic kidney disease (CKD). The aim of this work was to correlate parathyroid hormone (PTH) levels with urinary magnesium excretion in patients with non-dialysis dependent CKD. Methods Cross-sectional study. Concentrations of creatinine, magnesium, calcium, phosphate, parathyroid hormone (PTH), 25-hydroxyvitamin D [25(OH)D] and alkaline phosphatase (ALP) were determined in blood samples. The assessment of urinary magnesium levels was performed by means of total daily excretion and by the excretion fraction (FEMg). Results The study evaluated 163 patients with a mean age of 60.7 ± 11.7 years and 51.0% were male. In the highest quartile of PTH (>89.5pg/mL), the mean levels of FEMg and ALP were higher (p
Databáze: OpenAIRE