Synthesis of 8-oxoprotoberberines using acid-mediated cyclization or the Heck reaction

Autor: Xianwen Gan, Min Lei, Hankun Zhang, Kun Zhao, Lihong Hu, Anfeng Chen
Rok vydání: 2011
Předmět:
Zdroj: Monatshefte für Chemie - Chemical Monthly. 143:825-830
ISSN: 1434-4475
0026-9247
DOI: 10.1007/s00706-011-0656-6
Popis: A facile method of synthesizing 8-oxoprotoberberines is described from 6-benzoyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline-5-carbaldehyde via acid-mediated cyclization or from 2-(2-iodophenethyl)isoquinolin-1(2H)-one via the Heck reaction. The present method offers several advantages, such as good yields and a simple procedure.
Databáze: OpenAIRE