Synthesis of 8-oxoprotoberberines using acid-mediated cyclization or the Heck reaction
Autor: | Xianwen Gan, Min Lei, Hankun Zhang, Kun Zhao, Lihong Hu, Anfeng Chen |
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Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Monatshefte für Chemie - Chemical Monthly. 143:825-830 |
ISSN: | 1434-4475 0026-9247 |
DOI: | 10.1007/s00706-011-0656-6 |
Popis: | A facile method of synthesizing 8-oxoprotoberberines is described from 6-benzoyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline-5-carbaldehyde via acid-mediated cyclization or from 2-(2-iodophenethyl)isoquinolin-1(2H)-one via the Heck reaction. The present method offers several advantages, such as good yields and a simple procedure. |
Databáze: | OpenAIRE |
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