Hepatitis C Virus Infection, Linxian, China1
| Autor: | Sanford M. Dawsey, Lara Wong, Mingdong Zhang, Xiu-Di Sun, Steven D. Mark, Philip R. Taylor, Joseph F. Fraumeni, Wen Chen, You-Lin Qiao, Thomas R. O'Brien |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Epidemiology Hepacivirus Hepatitis C virus Population medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Immunoblot Assay 030212 general & internal medicine China education education.field_of_study biology business.industry virus diseases Hepatitis C Hepatitis B medicine.disease biology.organism_classification Virology Confidence interval 3. Good health Infectious Diseases 030211 gastroenterology & hepatology business |
| Zdroj: | Emerging Infectious Diseases. 11:17-21 |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | Bloodborne viruses may have spread in rural China during the past 25 years, but population-based prevalence estimates are lacking. We examined the frequency of hepatitis C virus (HCV) and HIV type 1 (HIV-1) among residents of Linxian, a rural community in Henan Province. In 2000, blood was collected from participants (> or = 55 years of age) who had enrolled in a population-based nutritional intervention trial in 1985. We randomly selected 500 participants for HCV testing and 200 participants for HIV-1 testing. For HCV, 48 (9.6%) of 500 participants were positive by enzyme immunoassay and recombinant immunoblot assay (95% confidence interval, 7.0%-12.2%), and prevalence was lowest in the most geographically isolated participants. Among the HCV-infected participants, 42 had a specimen available from 1985, of which 16 (38.1%) were positive for HCV. For HIV-1, 0/200 participants were positive. We conclude that HCV is now a common infection among older adults in Linxian, China. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|