Quantity of cholesterol extracted from the human skin surface: A possible discriminant of atherosclerosis?

Autor:	Yu. M. Lopukhin, T. I. Borkunova, E. S. Fortinskaya, T. I. Torkhovskaya, Khalilov Em, Markin Ss
Rok vydání:	1992
Předmět:	Plasma lipoprotein medicine.medical_specialty chemistry.chemical_compound Endocrinology Chemistry Cholesterol Internal medicine medicine Human skin General Medicine Positive correlation General Biochemistry Genetics and Molecular Biology
Zdroj:	Bulletin of Experimental Biology and Medicine. 113:645-648
ISSN:	1573-8221 0007-4888
Popis:	Basing on the data of Bouissou et al. on an increase of cholesterol content in the skin biopsies in atherosclerosis patients, the cholesterol amount was evaluated after superficial atraumatic rapid treatment of patients palm skin. The optimization of the extraction conditions was performed: the surface skin cholesterol value was constant for individual subjects (variability factor 5%). The range of this value was 1.5-6 Mg/cm2 and it was higher for atherosclerotic patients. No correlations with any conventional plasma lipoprotein parameters were observed. At the same time positive correlation (r = 0.54. p < 0.01) was observed with dyslipoprotein coefficient--(Ch+TG/alpha-Ch). Possible diagnostic significance of this skin cholesterol parameter is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d190893a7f63de9b5b4d6feecf82af0a https://doi.org/10.1007/bf00783745 Zobrazit plný text záznamu Full text from SpringerLink