The terpenyl pyrophosphates of wild type and tetraterpene mutants ofNeurospora crassa

Autor: S.C. Kushwaha, R. L. Renaud, Morris Kates, R. E. Subden
Rok vydání: 1978
Předmět:
Zdroj: Lipids. 13:352-355
ISSN: 1558-9307
0024-4201
DOI: 10.1007/bf02533727
Popis: Mutations to two albino loci ofNeurospora (al-2 andal-3) are known to block tetraterpene synthesis prior to phytoene but after farnesyl pyrophosphate. Analysis of the terpenyl pyrophosphates labeled with [214C] mevalonic acid revealed the presence of radioactive prephytoene, pyrophosphate in both albino mutants and in the corresponding wild type strain. Theal-2 andal-3 mutations are thus associated with lesions between prephytoene pyrophosphate and phytoene.
Databáze: OpenAIRE