Increased Oral Porphyromonas gingivalis Prevalence in Cardiovascular Patients with Uncontrolled Diabetes Mellitus
| Autor: | Yuichi Izumi, Mitsuaki Isobe, Yuka Shiheido, Norio Aoyama, Naho Kobayashi, Tomoya Hanatani, Jun-ichi Suzuki, Asuka Yoshida, Norihiko Ashigaki, Hiroki Sato |
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| Rok vydání: | 2018 |
| Předmět: |
Periodontitis
medicine.medical_specialty biology business.industry Bleeding on probing 030206 dentistry General Medicine Disease 030204 cardiovascular system & hematology medicine.disease biology.organism_classification Gastroenterology stomatognathic diseases 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus Epidemiology medicine medicine.symptom Risk factor Cardiology and Cardiovascular Medicine business Porphyromonas gingivalis Periodontopathic bacteria |
| Zdroj: | International Heart Journal. 59:802-807 |
| ISSN: | 1349-3299 1349-2365 |
| Popis: | The aim of this study was to determine the correlation between periodontopathic bacteria and diabetes mellitus (DM) status in cardiovascular disease (CVD) subjects.DM is associated with the progression of periodontitis. Several epidemiological studies have suggested that periodontitis may be a risk factor for CVD. However, no study has compared the periodontal condition between well-controlled and poorly-controlled DM patients with CVD.The subjects were well-controlled (n = 73) or poorly-controlled (n = 39) DM patients with CVD. Blood examinations and dental clinical measurements, including number of teeth, probing pocket depth, bleeding on probing (BOP), and clinical attachment level (CAL) were performed. Periodontopathic bacterial existence was evaluated.Worsened CAL and BOP rate were detected in the uncontrolled DM group compared to the controlled group. We found increased salivary Porphyromonas gingivalis counts in the uncontrolled DM group compared to well-controlled DM subjects.Specific periodontopathic bacterial infection may affect DM condition in CVD patients. |
| Databáze: | OpenAIRE |
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