Quantitative Assessment of Myocardial 99mTc-sestamibi Uptake During Exercise
| Autor: | Junya Chiba, Hitonobu Tomoike, Satomi Fujiwara, Yasuchika Takeishi, Hiroyuki Atsumi, Kazuei Takahashi |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Response rate (survey)
medicine.diagnostic_test Physiology business.industry medicine.disease Technetium (99mTc) sestamibi Isotopes of technetium Coronary artery disease Coronary arteries Myocardial perfusion imaging medicine.anatomical_structure Technetium-99 Medicine Cardiology and Cardiovascular Medicine business Nuclear medicine Rest (music) medicine.drug |
| Zdroj: | Japanese Circulation Journal. 62:592-598 |
| ISSN: | 1347-4839 0047-1828 |
| DOI: | 10.1253/jcj.62.592 |
| Popis: | An increase of 99mTc-sestamibi uptake in the myocardium during exercise was defined as a response rate, and the feasibility of a response rate for detecting coronary artery disease (CAD) was tested. Eighty-seven patients with suspected CAD had myocardial perfusion imaging with 99mTc-sestamibi during exercise and at rest. A dose of 370 MBq of 99mTc-sestamibi was injected at the maximal level of exercise, and a myocardial image was obtained 90 min later (exercise image). Then, 740 MBq of 99mTc-sestamibi was administered at rest, and myocardial imaging was repeated (rest image). The exercise and rest images were corrected for physical decay and injected doses, and the exercise image was subtracted from the rest image to obtain the corrected rest image. A response rate was calculated as follows: (exercise image - corrected rest image)×100/corrected rest image (%). The global response rates of 20 patients without significant coronary stenosis (≤50%) were higher than those of 67 patients with significant coronary stenosis (81 ±33% and 50±28%, p |
| Databáze: | OpenAIRE |
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