Periodontal inflammation correlates with systemic inflammation and insulin resistance in patients with recent diagnosis of type 2 diabetes
| Autor: | Natacha Oyarzo, Víctor Cortés, María Eugenia Riveros, Jessica Liberona, Constanza Andaur |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Periodontitis
medicine.medical_specialty biology business.industry Insulin medicine.medical_treatment Bleeding on probing C-reactive protein nutritional and metabolic diseases General Medicine Type 2 diabetes medicine.disease Gastroenterology chemistry.chemical_compound Insulin resistance chemistry Internal medicine Diabetes mellitus medicine biology.protein Glycated hemoglobin medicine.symptom business |
| Zdroj: | ARS MEDICA Revista de Ciencias Médicas. 44:6-12 |
| ISSN: | 0719-1855 0718-1051 |
| DOI: | 10.11565/arsmed.v44i1.1524 |
| Popis: | Background: diabetes and periodontitis are common comorbidities; however, the clinical implications of this association remain only partially known. This study was aimed to characterize the periodontal status of type 2 diabetic (T2D) patients and its correlation with metabolic and inflammatory parameters. Methods: patients (n = 30) with 5 or less years since the diagnosis of T2D (18 – 65 years old) were recruited. Anthropometric (Body Mass Index, BMI), metabolic (fasting glucose, glycated hemoglobin, insulin, HOMA-IR, HDL, LDL and total cholesterol, triglycerides) and inflammatory parameters (ultrasensitive C reactive protein, usCRP) were quantified. Periodontal evaluation included clinical attachment level (CAL), probing depth (PD), gingival level (GL) and bleeding on probing (BOP) average. Statistical significance was assessed by Mann-Whitney and Spearman correlation tests. Results: mean values of BOP, CAL, PD and GL were 39.3, 2.8, 2.8, and 0.1, respectively. BOP significantly correlated with BMI and HOMA-IR and was higher in patients with elevated usCRP >3 mg/L (p |
| Databáze: | OpenAIRE |
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