| Popis: |
The spinal cord and its interactions with the brain are fundamental for movement control and somatosensation. However, brain and spinal cord electrophysiology in humans have largely been treated as distinct enterprises, in part due to the relative inaccessibility of the spinal cord. Consequently, there is a dearth of knowledge on human spinal electrophysiology, including the multiple pathologies of the central nervous system that affect the spinal cord as well as the brain. Here we exploit recent advances in the development of wearable optically pumped magnetometers (OPMs) which can be flexibly arranged to provide coverage of both the spinal cord and the brain concurrently in unconstrained environments. Our system for magnetospinoencephalography (MSEG) measures both spinal and cortical signals simultaneously by employing a custom-made spinal scanning cast. We evidence the utility of such a system by recording simultaneous spinal and cortical evoked responses to median nerve stimulation, demonstrating the novel ability for concurrent non-invasive millisecond imaging of brain and spinal cord. |
