Halogen mobility in S N2 reactions of carbonyl compounds. Comparisons with aromatic halogen mobility

Autor:	Oi-Ling Ying, Joseph Miller
Rok vydání:	1985
Předmět:	organic chemicals Inorganic chemistry chemistry.chemical_element Halide Medicinal chemistry Chloride chemistry.chemical_compound chemistry Halogen Fluorine medicine SN2 reaction Reactivity (chemistry) Solvolysis Fluoride medicine.drug
Zdroj:	Journal of the Chemical Society, Perkin Transactions 2. :323
ISSN:	1364-5471 0300-9580
Popis:	Kinetic studies, using conductimetric techniques, have been carried out for isopropanolysis (solvolysis) reactions of some alkanoyl, benzoyl, and perfluoroalkanoyl halides, viz. butanoyl and benzoyl fluorides, chlorides, and bromides and perfluoropentanoyl fluoride and chloride. The halogen mobility orders, F Cl < Br, have been compared with mobility patterns recognised for SN reactions at saturated and aromatic carbon, and have been discussed in mechanistic terms. The substrate class reactivity order is perfluoroalkanoyl benzoyl, alkanoyl. The actual ratios depend on which halogen is displaced, the ratios being larger in displacement of fluorine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d1452f01242727470af7e038e20be82a https://doi.org/10.1039/p29850000323 Zobrazit plný text záznamu