Computational Methods for Cardiac Electromechanics

Autor:	Roy C. P. Kerckhoffs, Andrew D. McCulloch, Sarah N. Healy, Taras P. Usyk
Rok vydání:	2006
Předmět:	Cellular mechanism Engineering business.industry Cardiac electrophysiology Efficient algorithm Molecular mechanism Control engineering Numerical models Electrical and Electronic Engineering business Cardiac mechanics Electromechanics Simulation
Zdroj:	Proceedings of the IEEE. 94:769-783
ISSN:	1558-2256 0018-9219
Popis:	Computational modeling provides a potentially powerful way to integrate structural properties measured in vitro to physiological functions measured in vivo. Focusing on the various scales (cell-tissue-organ-system), we give an overview of the importance and applications of numerical models of ventricular anatomy, electrophysiology, mechanics, and circulatory models. The integration of these models in one multiscale model of cardiac electromechanics is discussed in the light of applications to hypothesis generation, diagnosis, surgery(planning, training, and outcome of interventions), and therapies. Special attention is paid to practical use in terms of computational demand. Because of growing computer power and the development of efficient algorithms, we expect that real-time simulations with multiscale models of cardiac electromechanics become feasible in 2008 (despite the increasing complexity of models due to data accumulation on molecular and cellular mechanisms).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d1427d9c4093af2598323c848f57aa8b https://doi.org/10.1109/jproc.2006.871772 Zobrazit plný text záznamu