Controlling Hypertension after Severe Cerebrovascular Event (CHASE): A Randomised, Multicentre, Controlled Study

Autor: Fang Yuan, Fang Yang, Jingjing Zhao, Feng Fu, Yi Liu, Changhu Xue, Kangjun Wang, Xiangjun Yuan, Dingan Li, Qiuwu Liu, Wei Zhang, Yi Jia, Jianbo He, Jun Zhou, Xiaocheng Wang, Hua Lv, Kang Huo, Zhuanhui Li, Bei Zhang, Chengkai Wang, Li Li, Hongzeng Li, Wen Jiang, CHASE Study Group
Rok vydání: 2019
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
DOI: 10.2139/ssrn.3363799
Popis: Background: The optimal BP-lowering target in the acute phase of severe stroke is uncertain. We aimed to compare the efficacy and safety of individualised BP lowering with standard BP lowering in severe stroke. Methods: We conducted a randomised, multicentre study in 26 hospitals in China. Eligible patients were randomised into an individualised BP-lowering group (with 10-15% reduction in systolic BP [SBP] from admission level) or standard BP-lowering group (with a target SBP of
Databáze: OpenAIRE