ChemInform Abstract: Studies Toward the Total Synthesis of RP-66453

Autor:	Sabine Boisnard, Jieping Zhu
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Bicyclic molecule Chemistry medicine.drug_class Stereochemistry medicine Total synthesis Ether General Medicine Ring (chemistry) Receptor antagonist Unit (ring theory)
Zdroj:	ChemInform. 33
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200229228
Popis:	Synthesis of a bicyclic A-B-O-C ring system of RP-66453 (I), a neurotensine receptor antagonist, with an endo aryl-aryl and an endo aryl-aryl ether bond is described. An alternative synthetic strategy starting from the construction of functionalized B-O-C cycloisodityrosine unit is also detailed. [on SciFinder (R)]
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d13fe75049d5e6012c3ec470c5ff306b https://doi.org/10.1002/chin.200229228 Zobrazit plný text záznamu Plný text