Analyzing inter-individual shape variations of the middle ear cavity by developing a common shape model based on medial representation

Autor: Karl D. Fritscher, Christian Habermann, Rainer Schubert, Roland Pilgram, Rudolf Leuwer, Anne Müller
Rok vydání: 2004
Předmět:
Zdroj: CARS
ISSN: 0531-5131
DOI: 10.1016/j.ics.2004.03.190
Popis: Analysis of shape variability of anatomical structures is a widespread problem on one hand and an essential fundament for the analysis of biological processes and the diagnosis of a large spectrum of pathologies on the other hand. Many diseases affecting the middle ear result from morphological alterations and provoke morphological changes of the middle ear cavity. Therefore, it was our goal to analyze shape and shape variations of a population of this anatomical structure.By segmenting and modeling 10 middle ear cavities using a medial-based representation, which provides inter-individual correspondence, a common shape model of the tympanic cavity has been generated. The results show that medial-based representation is suitable to generate a common shape model of the tympanic cavity and to provide a facility to analyze the complex shape of the anatomical structure and the physiological variations.
Databáze: OpenAIRE