Radiosynthesis of ( R , S )‐[ 18 F]GE387: A Potential PET Radiotracer for Imaging Translocator Protein 18 kDa (TSPO) with Low Binding Sensitivity to the Human Gene Polymorphism rs6971

Autor:	Franklin I. Aigbirhio, David J. Williamson, Xiouyun Zhou, Michael Kassiou, Eryn L. Werry, Luxi Qiao, Emily Fisher, Saijinder Luthra, Nisha Kuzhuppilly-Ramakrishnan, William Trigg, Matthew Hird, Selena Milicevic Sephton, Lindsay McMurray
Rok vydání:	2019
Předmět:	Pharmacology biology business.industry Organic Chemistry Radiosynthesis Pet imaging Biochemistry Molecular biology Drug Discovery Translocator protein biology.protein Molecular Medicine Medicine Gene polymorphism General Pharmacology Toxicology and Pharmaceutics business
Zdroj:	ChemMedChem. 14:982-993
ISSN:	1860-7187 1860-7179
Popis:	This work was supported by Medical Research Council (UK) grant awards RG46503 (LM, MH, XZ) and RG70550 (EF), National Institute of Health Research (UK), Cambridge Biomedical Research Unit in Dementia (EF, NKR) and the Herchel Smith Fellowship programme (LQ).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d10da184470c7142fee35bf39694c109 https://doi.org/10.1002/cmdc.201900023 Zobrazit plný text záznamu Plný text