Characterization of peak purity by fast multiscan circular dichroism detection

Autor:	A. Gergeley, B. Noszál, Peter Horvath
Rok vydání:	1998
Předmět:	Analyte Circular dichroism Chromatography Spectrometer Chemistry Organic Chemistry Clinical Biochemistry Detector Analytical chemistry Biochemistry Spectral line Analytical Chemistry Characterization (materials science) Sensitivity (control systems) Selectivity
Zdroj:	Chromatographia. 48:584-588
ISSN:	1612-1112 0009-5893
Popis:	A method has been developed to detect inhomogeneity of apparently homogeneous peaks of very similar analytes. The method utilizes the rapid scan feature of state-of-the-art spectrometers/detectors that allow the recording of up to 30 spectra in a single chromatographic peak. Sensitivity and selectivity are enhanced by chiroptical/optical detection. Thus, identification of “front” and “rear” components of the peak can be carried out. The method is exemplified by mixtures of codeine, hydrocodone and oxycodone as analytes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d0fe2aa633551fcab80b5ad22e741eb5 https://doi.org/10.1007/bf02466654 Zobrazit plný text záznamu Full text from SpringerLink