| Autor: | Masahito Taya, Motomu Nishioka, Takuro Nishimura, Akira Ookubo |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Zirconium
Chemistry Inorganic chemistry chemistry.chemical_element Bioengineering General Medicine Sterilization (microbiology) medicine.disease_cause Applied Microbiology and Biotechnology chemistry.chemical_compound Adsorption Zirconium phosphate Chlorine medicine Moiety Escherichia coli Biotechnology Antibacterial agent |
| Zdroj: | Biotechnology Letters. 25:1263-1266 |
| ISSN: | 0141-5492 |
| DOI: | 10.1023/a:1025031111800 |
| Popis: | Silver-loaded zirconium phosphate (AgZ) was combined with hydroxyapatite (HA) to prepare an antibacterial composite (AgZ/HA) with improved activity in the presence of Cl-. When Escherichia coli cells were deactivated in 154 mM NaCl, the bacterial survival ratio at 90 min for AgZ/HA was 3.9 x 10(-4) compared to 1.2 x 10(-1) for AgZ itself. Because the bactericidal activity of AgZ/HA decreased with increasing phosphate ion up to 10 mM, cell adsorption onto the combined HA moiety probably compensated for the Cl- -induced deterioration in the activity of the silver-based bactericide. |
| Databáze: | OpenAIRE |
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