Expand+In Vivoiv.iiarjournals.orgIn Vivo September-October 2017 vol. 31 no. 5 925-930 Parathyroid Carcinoma in Patients that Have Undergone Surgery for Primary Hyperparathyroidism
| Autor: | Martina Fialová, Ondřej Naňka, Robert Lischke, Vladimir Bobek, Josef Kubinyi, Jiří Šedý, Adámek S, Broulík P, Pavel Pafko, P Libánský |
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| Rok vydání: | 2018 |
| Předmět: |
Pharmacology
Cancer Research medicine.medical_specialty Hyperparathyroidism business.industry Recurrent Laryngeal Nerve Injury 030209 endocrinology & metabolism medicine.disease General Biochemistry Genetics and Molecular Biology Surgery 03 medical and health sciences 0302 clinical medicine Parathyroid carcinoma 030220 oncology & carcinogenesis Primary operation medicine In patient business Survival rate Primary hyperparathyroidism |
| Zdroj: | In Vivo. 31 |
| ISSN: | 1791-7549 |
| Popis: | BACKGROUND/AIM Parathyroid carcinoma is a rare clinical entity, which represents one of the main reasons, why surgery should be performed in specialized centres. Preoperatively, it is very difficult to distinguish between benign and malignant hyperparathyroidism. PATIENTS AND METHODS During the years 1996-2016, we performed 2,220 operations in 2,075 patients with a diagnosis of primary hyperparathyroidism. RESULTS Among these 2,220 operations, there were 16 operations for parathyroid carcinoma. These 16 operations, including reoperations, were performed in four patients. Two patients had no reoperation, but another 2 patients required 14 reoperations in total. Parathyroid carcinoma was described in 0.2% of all patients with a diagnosis of primary hyperparathyroidism. The number of operations was 0.73% of all operations of primary hyperparathyroidism in years 1996-2016. CONCLUSION Prognosis of parathyroid carcinoma is quite favourable, patients evidence a long-term survival rate after the primary operation. However, every reoperation increases the number of possible complications, including recurrent laryngeal nerve injury. |
| Databáze: | OpenAIRE |
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