Evaluation of the hemocompatibility of hydrated biodegradable aliphatic carbonyl polymers with a subtle difference in the backbone structure based on the intermediate water concept and surface hydration

Autor: Kazuki Fukushima, Yuto Inoue, Yuta Haga, Masaru Tanaka, Kodai Matsuzaki, Meng Yu Tsai, Takayuki Ota
Rok vydání: 2015
Předmět:
Zdroj: Polymer Journal. 47:469-473
ISSN: 1349-0540
0032-3896
DOI: 10.1038/pj.2015.22
Popis: The hydration behavior, intermediate water content and platelet adhesion level of four different aliphatic carbonyl polymers that have subtle differences in the backbone structure were investigated. The platelet adhesion was strongly related to the surface hydration and intermediate water content for the hydrated polymers. The ether bonds in the main chain has a significant role in hydration and poly(p-dioxanone) exhibits the lowest platelet adhesion level among four polymers. The other three polymers showed similar platelet adhesion levels. However, carbonate bonds contribute to the formation of more intermediate water than ester bonds.
Databáze: OpenAIRE