Chemotherapy of disseminated gastric cancer. A joint effort of the Northern California oncology group and the Japanese gastric cancer chemotherapy group

Autor:	Kioji Kimura, Yoshio Sakurai, Stephen K. Carter, Michael A. Friedman, Makoto Ogawa, John F. Hannigan
Rok vydání:	1983
Předmět:	Oncology Cancer Research medicine.medical_specialty Chemotherapy Cancer chemotherapy Performance status business.industry medicine.medical_treatment Cancer Extent of disease Combination chemotherapy medicine.disease Gastric adenocarcinoma Internal medicine medicine business Median survival
Zdroj:	Cancer. 52:1771-1777
ISSN:	1097-0142 0008-543X
DOI:	10.1002/1097-0142(19831115)52:10<1771::aid-cncr2820521002>3.0.co;2-u
Popis:	A consortium of Northern California and Japanese investigators studied 142 patients with advanced gastric adenocarcinoma. Patients were randomized to one of two combination chemotherapy programs in each nation (one common therapy shared and one therapy unique to each nation). Median duration of survival ranged between 5 and 45 weeks, depending on performance status, extent of disease, and chemotherapy program. More importantly, there was considerable comparability with respect to toxicity and outcome between patients in the US and Japan. Overall median survival was 26 weeks for Japanese and 27 weeks for US patients. This study helps provide the basis for future comparative multinational trials.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d0ae3c34e9ad38abd6e3cdc9a06bec5f https://doi.org/10.1002/1097-0142(19831115)52:10<1771::aid-cncr2820521002>3.0.co Zobrazit plný text záznamu Plný text