Long-term follow-up of treated and untreated hyperprolactinaemic patients

Autor: Marc Dhont, G. Kermans, D. Vandekerckhove
Rok vydání: 1985
Předmět:
Zdroj: Journal of Obstetrics and Gynaecology. 5:174-181
ISSN: 1364-6893
0144-3615
DOI: 10.3109/01443618509067744
Popis: SummaryThe clinical and endocrine course of 43 hyperprolactinaemic women, followed for a median period of 48 months, was analysed. A tentative distinction between hyperprolactinaemia with and without pituitary tumour was made by a plain lateral and frontal radiograph of the skull, supplemented by tomography of the sella when indicated. Seventeen women had radiological evidence of a pituitary adenoma. Serum prolactin levels in this group were significantly higher than those from women with normal radiological findings, but the presenting clinical symptoms were comparable in both groups. Twelve of our 43 patients received no treatment, 25 patients were treated with bromocriptine for 1 to 48 months and 6 patients were treated with a combination of bromocriptine, radiotherapy and surgery. Twenty six conceptions and 20 full-term pregnancies were achieved. Complications due to pituitary tumour growth during pregnancy occurred in one patient. Cure of hyperprolactinaemia was observed in 3 patients treated with br...
Databáze: OpenAIRE