Stéréosélectivité de l'addition de réactifs nucléophiles sur des cétones polycycliques à jonction trans

Autor:	P. Maroni, A. Accary, L. Gorrichon-Guigon, R. Barret, D. Calmes, J. Huet
Rok vydání:	1981
Předmět:	chemistry.chemical_compound Nucleophile Chemistry Stereochemistry Organic Chemistry Drug Discovery Ring (chemistry) Biochemistry Carbonyl group Group 2 organometallic chemistry
Zdroj:	Tetrahedron. 37:879-885
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)97654-9
Popis:	The nucleophilic additions of hindered organometallic compounds to polycyclic ketones with trans ring junctions involve predominant axial attack when flattening of the ring containing the carbonyl group occurs. The influence of nucleophile structure (O-Por C-metallated character) on equatorial or axial attack is discussed.
Databáze:	OpenAIRE
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