New practical access to 2-azatryptophans and dehydro derivatives via the Wittig–Horner reaction

Autor:	François Crestey, Valérie Collot, Silvia Stiebing, Jana Sopkova-de Oliveira Santos, Jean-François Lohier, Sylvain Rault
Rok vydání:	2007
Předmět:	chemistry.chemical_classification Indazole chemistry.chemical_compound Stereochemistry Chemistry Organic Chemistry Drug Discovery Wittig reaction Organic chemistry Biochemistry Amino acid
Zdroj:	Tetrahedron Letters. 48:2457-2460
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2007.02.042
Popis:	The Wittig–Horner reaction of protected 3-formylindazoles 1 with (±)-N-(benzyloxycarbonyl)-α-phosphonoglycine trimethyl ester 2 has been developed as a new practical synthesis of dehydro 2-azatryptophans and amino acid derivatives. The preparation of 5-bromo-3-formylindazole is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d08f1d63281be9a58363dfa71bed9071 https://doi.org/10.1016/j.tetlet.2007.02.042 Zobrazit plný text záznamu Full Text from ScienceDirect