Effect of Ursodeoxycholic Acid Administration in Patients with Primary Hypercholesterolaemia
| Autor: | Camilla Cicognani, Antonio Maria Morselli-Labate, Raffaella Talarico, Mauro Malavolti, Claudia Sama, L Zamboni |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Bile acid business.industry medicine.drug_class Cholesterol General Medicine medicine.disease Gastroenterology Ursodeoxycholic acid Coronary artery disease chemistry.chemical_compound Primary biliary cirrhosis Endocrinology Pharmacotherapy chemistry Oral administration Internal medicine medicine lipids (amino acids peptides and proteins) Pharmacology (medical) business medicine.drug Lipoprotein |
| Zdroj: | Clinical Drug Investigation. 18:263-269 |
| ISSN: | 1173-2563 |
| DOI: | 10.2165/00044011-199918040-00002 |
| Popis: | Objective: A high plasma cholesterol level is a major predisposing factor for coronary artery disease, and new treatments are currently under consideration. Supported by the close relationship between cholesterol and bile acid metabolism, recent studies have reported a hypocholesterolaemic effect of the bile acid ursodeoxycholic acid (UDCA) in patients with primary biliary cirrhosis but, unfortunately, no data are available in primary hypercholesterolaemia. We performed this study to evaluate the effects of oral administration of UDCA on serum lipoprotein patterns in patients with primary hypercholesterolaemia. |
| Databáze: | OpenAIRE |
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