Microwave-assisted Suzuki–Miyaura cross-coupling of 2-alkyl and 2-alkenyl-benzo-1,3,2-diazaborolanes

Autor:	Siphamandla Sithebe, Siphamandla W. Hadebe, Ross S. Robinson
Rok vydání:	2011
Předmět:	chemistry.chemical_classification Silicon Organic Chemistry chemistry.chemical_element Biochemistry Nitrogen Coupling reaction Hydroboration chemistry Suzuki reaction Drug Discovery Polymer chemistry Organic chemistry Reactivity (chemistry) Microwave Alkyl
Zdroj:	Tetrahedron. 67:4277-4282
ISSN:	0040-4020
DOI:	10.1016/j.tet.2011.03.095
Popis:	Nitrogen-based boronate esters, such as 2-octyl-benzo-1,3,2-diazaborolane, 2-phenethyl-benzo-1,3,2-diazaborolane, and 2-{(1E)-hexenyl}-benzo-1,3,2-diazaborolane have been shown to be suitable coupling partners with arylhalides in microwave accelerated Suzuki cross-coupling reactions. Reaction yields of up to 89% were achieved. The use of a silicon group attached to the nitrogen atom, proved to enhance the reactivity of 2-octyl-benzo-1,3,2-diazaborolane.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d06475879c6707ab251a0382d017a9c2 https://doi.org/10.1016/j.tet.2011.03.095 Zobrazit plný text záznamu Full Text from ScienceDirect