An unusual cause of hyperinsulinaemic hypoglycaemia syndrome
Autor: | P. L. Drury, I. M. Holdaway, Patrick J. Manning, E. A. Espiner, K. Yoon, A. Bowers |
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Rok vydání: | 2003 |
Předmět: |
endocrine system
medicine.medical_specialty Pancreatic disease endocrine system diseases business.industry Endocrinology Diabetes and Metabolism Calcium stimulation test Stimulation Hypoglycemia medicine.disease Hyperinsulinaemic hypoglycaemia Endocrinology Internal medicine Insulin response Internal Medicine medicine Hyperinsulinemia business Insulinoma hormones hormone substitutes and hormone antagonists |
Zdroj: | Diabetic Medicine. 20:772-776 |
ISSN: | 0742-3071 |
DOI: | 10.1046/j.1464-5491.2003.01033.x |
Popis: | Endogenous hyperinsulinism as a cause for hypoglycaemia can be attributed to a number of different causes including insulinoma, sulphonylurea drugs and the newly described disorder non-insulinoma pancreatogenous hypoglycaemia (NIPH). The calcium stimulation test is increasingly used as a method for not only localizing insulinoma but also for distinguishing the above entities. We describe a case in which felonious sulphonylurea administration was used to mimic either an insulinoma or NIPH. Importantly, this case demonstrates that, contrary to previous reports, the insulin response to calcium stimulation in such cases may be uniformly positive and should alert the physician to possible surreptitious sulphonylurea ingestion. |
Databáze: | OpenAIRE |
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