DNA modifications and genome rearrangements during the development and sex differentiation of the bumble bee Bombus terrestris
| Autor: | G. Jegot, Sophie Casteret, J.-N. Tasei, P. Aupinel, Yves Bigot |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Genetics
Transposable element 0303 health sciences Sexual differentiation 030302 biochemistry & molecular biology Gene rearrangement Biology biology.organism_classification Genome 03 medical and health sciences Insect Science Bombus terrestris DNA methylation Molecular Biology Gene 030304 developmental biology Genomic organization |
| Zdroj: | Insect Molecular Biology. 20:165-175 |
| ISSN: | 0962-1075 |
| DOI: | 10.1111/j.1365-2583.2010.01052.x |
| Popis: | Bombus terrestris is a bumble bee that, like most hymenopteran species, exhibits ploidy-specific sex determination controlled by a single sex gene. Depending on their ploidy and the queen pheromone repression, the imagoes differentiate into three castes: males, workers and queens. Here, we focus on the differences of genome organization that occur during development and sex differentiation. We found that cytosine methylation is a significant epigenetic factor with profiles that can be correlated with both processes. We also showed that two kinds of genomic rearrangement occur. The first consists of important DNA amplifications that have sequence profiles that differ in the different developmental instars and sexes. In the second kind, DNA losses also occur, at least involving the mosaic transposable element B. terrestris mosaic repeat 1 (BTMR1). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text