ChemInform Abstract: A Potential Antiprotozoal Drug Containing Acridine and Thiadiazole Moieties

Autor:	P. Amiel, Pierre Brouant, A. Mrozek, Janina Karolak-Wojciechowska, Jacques Barbe
Rok vydání:	2010
Předmět:	Steric effects Drug medicine.drug_class Chemistry Stereochemistry media_common.quotation_subject Acridine derivatives General Medicine Medicinal chemistry chemistry.chemical_compound Acridine Antiprotozoal medicine Antiprotozoal Drugs media_common
Zdroj:	ChemInform. 28
ISSN:	0931-7597
DOI:	10.1002/chin.199714039
Popis:	The title compound, 3-(6-chloro-2-methoxy-9-acridinyl)-5-[2-(diethylamino)ethylthio]-1,3,4-thiadiazol-2(3H)-one, C 22 H 23 ClN 4 OS 3 , belongs to a series of new potential antiprotozoal drugs containing the acridine and thiadiazole systems. These two quasi-planar moieties are bonded together and are almost perpendicular to one another because of steric hindrance.
Databáze:	OpenAIRE
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