Supercritical Fluid Treatment of Three-Dimensional Hydrogel Matrices Obtained from Allylchitosan by Laser Stereolithography

Autor: O. O. Parenago, M. A. Markov, K. N. Bardakova, A. M. Grigoryev, V. V. Lunin, Boris Shavkuta, Viktor N Bagratashvili, A. E. Lazhko, Tatiana A. Akopova, Petr Timashev, S. N. Churbanov
Rok vydání: 2018
Předmět:
Zdroj: Russian Journal of Physical Chemistry B. 12:1144-1151
ISSN: 1990-7923
1990-7931
Popis: The effect of the treatment of hydrogel matrices based on allyl-substituted chitosans and formed by laser stereolithography in supercritical carbon dioxide (SC-CO2) on their surface polarity and mechanical characteristics was studied. Treatment in a flow mode increased the mechanical stability of the materials due to the effective extraction of the low-molecular components and oligomers. The surface polarity of the matrix decreased, improving its biocompatibility. The hydrogel matrices treated in SC-CO2 have no cytotoxic activity, due to which they can be used in tissue engineering.
Databáze: OpenAIRE