Associations of accelerometer-measured physical activity and physical activity-related cancer incidence in older women: results from the WHI OPACH Study

Autor: Bellettiere, J., Parada, H., Jr., LaMonte, M.J., Evenson, K.R., McDonald, E., LaCroix, A.Z.
Jazyk: angličtina
Rok vydání: 2020
DOI: 10.17615/b419-zh26
Popis: Background: We examined the associations between accelerometry-measured physical activity (PA) and incidence of 13 cancers among a cohort of postmenopausal women. Methods: In this prospective study, 6382 women wore ActiGraph GT3X+ accelerometers at the hip for up to 7 days during 2012���2013, and were followed over a median of 4.7 years for diagnosis of 13 invasive cancers. Calibrated intensity cut points were used to define minutes per day of total, light and moderate-to-vigorous PA. We used multivariable Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for tertiles, and one-standard deviation (SD) unit increments of PA exposures in relation to cancer incidence. We examined effect measure modification by age, race/ethnicity, body mass index and smoking history. Results: The highest (vs. lowest) tertiles of total, light and moderate-to-vigorous PA were associated with covariate-adjusted HRs of 0.72 (95% CI = 0.53���0.97), 0.81 (95% CI = 0.60���1.09) and 0.66 (95% CI = 0.48���0.91), respectively. In age-stratified analyses, HRs for total PA were lower among women
Databáze: OpenAIRE