Uptake and transport of furanodiene in Caco-2 cell monolayers: a comparison study between furanodiene and furanodiene loaded PLGA nanoparticles
| Autor: | Dong-Hai Lin, Jun-Teng Wang, Li-Fang Qin, Xin-Xin Xie, Ke Liu, Gang Li |
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| Rok vydání: | 2013 |
| Předmět: |
Chemistry
Cell technology industry and agriculture Nanotechnology macromolecular substances General Medicine respiratory system Bioavailability Plga nanoparticles Solvent medicine.anatomical_structure Complementary and alternative medicine Chemical engineering Caco-2 Drug Discovery Lipophilicity Emulsion Monolayer medicine |
| Zdroj: | Chinese Journal of Natural Medicines. 11:49-55 |
| ISSN: | 1875-5364 |
| DOI: | 10.1016/s1875-5364(13)60007-2 |
| Popis: | Aim Furanodiene (FDE) possesses diverse pharmacological activities with high lipophilicity and poor stability. This study prepared FDE loaded PLGA nanoparticles (FDE-PLGA-NPs) and PEGylated PLGA nanoparticles (FDE-PEG-PLGA-NPs) by the spontaneous emulsion solvent diffusion method to improve the stability and bioavailability of FDE. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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