Comparison of Conventionally Measured Serum Bicarbonate Values with Bicarbonate Values Obtained in Arterial and Venous Blood Gas Analysis

Autor:	S Zabeen, N Houqe, W Nargis, Z Hossain, BU Ahamed
Rok vydání:	2013
Předmět:	medicine.medical_specialty business.industry Bicarbonate General Medicine Venous blood Intensive care unit Health centre law.invention Surgery chemistry.chemical_compound chemistry law Anesthesia medicine Arterial blood Arterial blood gas analysis Hospital patients business Serum bicarbonate
Zdroj:	Bangladesh Journal of Medical Biochemistry. 5:12-15
ISSN:	2408-8331 2073-9915
DOI:	10.3329/bjmb.v5i1.13425
Popis:	Bicarbonate (HCO 3 - ) measurement in serum or plasma from a sample of venous blood is routinely practiced in hospital patient management. HCO 3 - status can also be assumed from Blood gas analysis requiring arterial blood as sample which is cumbersome for both patients and doctors. This study was undertaken to evaluate the extent of agreement among biocarbonate values obtained during venous, arterial blood gas analysis and conventionally measured serum bicarbonate levels in a group of intensive care unit (ICU) patients to determine whether conventionally measured serum HCO 3 - (from peripheral venous blood) and calculated HCO 3 - values (from arterial blood gas [ABG] analyzers) can be used interchangeably. A total of 51 adult patients with diverse medical conditions, presenting at a tertiary health centre ICU were enrolled in this study when deemed by the treating physician to have an ABG analysis. Arterial and venous samples were taken as close in time as possible for blood gas analysis and routine blood tests. Bland-Altman analyses were used to compare the three methods. The HCO 3 - levels from ABG, Venous Blood gas (VBG) and tconventionally measured serum HCO 3 - showed acceptably narrow 95% limits of agreement using the Bland-Altman method. VBG reveals higher level of agreement with the ABG bicarbonate values compared to measured serum HCO 3 - . Thus, venous blood can be an alternate for arterial blood where ABG analyzer is available. conventionaly serum HCO 3 - measurements can also be useful and used as substitute for an expensive ABG analyzer in resource constrained health care sectors when required. DOI: http://dx.doi.org/10.3329/bjmb.v5i1.13425 Bangladesh J Med Biochem 2012; 5(1): 12-15
Databáze:	OpenAIRE
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