The effects of cold water immersion and active recovery on inflammation and cell stress responses in human skeletal muscle after resistance exercise
| Autor: | Jonathan M. Peake, James F. Markworth, Ingrid M. Egner, Simone Krog, Sigve Nyvik Aas, Truls Raastad, Llion A. Roberts, Katsuhiko Suzuki, David Cameron-Smith, Vandre C. Figueiredo, Jeff S. Coombes |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Physiology business.industry Skeletal muscle Inflammation CCL4 030229 sport sciences Hsp70 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Endocrinology Heat shock protein Internal medicine Hyperalgesia Immunology Medicine Tumor necrosis factor alpha Interleukin 8 medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | The Journal of Physiology. 595:695-711 |
| ISSN: | 0022-3751 |
| DOI: | 10.1113/jp272881 |
| Popis: | Cold water immersion and active recovery are common post‐exercise recovery treatments. However, little is known about whether these treatments influence inflammation and cellular stress in human skeletal muscle after exercise. We compared the effects of cold water immersion versus active recovery on inflammatory cells, pro‐inflammatory cytokines, neurotrophins and heat shock proteins (HSPs) in skeletal muscle after intense resistance exercise. Nine active men performed unilateral lower‐body resistance exercise on separate days, at least 1 week apart. On one day, they immersed their lower body in cold water (10°C) for 10 min after exercise. On the other day, they cycled at a low intensity for 10 min after exercise. Muscle biopsies were collected from the exercised leg before, 2, 24 and 48 h after exercise in both trials. Exercise increased intramuscular neutrophil and macrophage counts, MAC1 and CD163 mRNA expression (P < 0.05). Exercise also increased IL1β, TNF, IL6, CCL2, CCL4, CXCL2, IL8 and LIF mRNA expression (P < 0.05). As evidence of hyperalgesia, the expression of NGF and GDNF mRNA increased after exercise (P < 0.05). The cytosolic protein content of αB‐crystallin and HSP70 decreased after exercise (P < 0.05). This response was accompanied by increases in the cytoskeletal protein content of αB‐crystallin and the percentage of type II fibres stained for αB‐crystallin. Changes in inflammatory cells, cytokines, neurotrophins and HSPs did not differ significantly between the recovery treatments. These findings indicate that cold water immersion is no more effective than active recovery for reducing inflammation or cellular stress in muscle after a bout of resistance exercise. |
| Databáze: | OpenAIRE |
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