Facile Synthesis of Tricyclic Oxazino- or Oxazepino-Fused Tetrahydroquinolines via Intramolecular Reductive Amidation

Autor: Shyamal Kumar Mondal, Rupankar Paira, Saktipada Das, Arindam Maity, Nirup B. Mondal, Krishnendu B. Sahu, Sukdeb Banerjee, Abhijit Hazra, Subhendu Naskar, Pritam Saha
Rok vydání: 2011
Předmět:
Zdroj: Synthesis. 2011:2079-2084
ISSN: 1437-210X
0039-7881
DOI: 10.1055/s-0030-1260056
Popis: Reductive cyclization of w-(8-quinolyloxy)alkyl esters by zinc in acetic acid is shown to constitute a convenient methodology for the synthesis of oxazino- or oxazepino-fused tetrahydroquinolines. It is operationally simple, requires a short reaction time, and provides excellent yields.
Databáze: OpenAIRE