Histologic changes in the sinus membrane after maxillary sinus augmentation with simultaneous implant placement using engineered bone graft material

Autor: Wei Zhao, Xiao-hui Qu, Jia-yu Lu, Hong Zhu, De-rong Zou
Rok vydání: 2011
Předmět:
Zdroj: Journal of Shanghai Jiaotong University (Science). 16:380-384
ISSN: 1995-8188
1007-1172
DOI: 10.1007/s12204-011-1166-8
Popis: The aim of the study was to analyze the histologic and ultrastructural changes after maxillary sinus augmentation with simultaneous implant placement using engineered bone graft material. In this study, calcium phosphate cement (CPC) scaffolds combined with goat bone marrow stromal cells (BMSCs) were used to fill goat sinus floor space after maxillary sinus floor elevation with simultaneous implant placement comparing with those not filled any grafted materials and used as controls. After a healing period of 3 months, the goat maxillary sinus membrane was examined using light microscopy and scanning electronic microscopy. The results showed that the connective tissue thickness and the epithelium thickness of mucosa were not statistically significant difference between two groups. The tissue engineered bone complex might be an ideal graft for the sinus floor elevation and have no influence on the sinus membrane under the histological and ultrastructural observation.
Databáze: OpenAIRE