New diagnosis of bullous pemphigoid after withdrawal of immunosuppressive therapy in a failed renal transplant recipient on hemodialysis
| Autor: | Seyed Mehrdad Hamrahian, Litty Thomas, Amanda Quorles, Tibor Fülöp, Sohail Abdul Salim |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
integumentary system medicine.diagnostic_test business.industry medicine.drug_class medicine.medical_treatment Hematology medicine.disease Dermatology Discontinuation End stage renal disease 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Nephrology Prednisone Failed renal transplant Skin biopsy medicine Corticosteroid 030212 general & internal medicine Hemodialysis Bullous pemphigoid business medicine.drug |
| Zdroj: | Hemodialysis International. 22:E26-E32 |
| ISSN: | 1492-7535 |
| Popis: | The occurrence of the autoimmune blistering disease, bullous pemphigoid (BP), in patients with failed renal allograft is rare and the few reported cases suggest various provocative factors without reaching a consensus. Here we report the case of a patient presenting with bullous lesions soon after the complete discontinuation of immunosuppressant therapy following renal allograft failure. Skin biopsy confirmed the diagnosis of BP. Administration of systemic corticosteroid controlled the occurrence of BP lesions in our patient. Increased clinical suspicion is warranted in cases of patients with renal transplant failure, since withdrawal of the immunosuppressant therapy could lead to unmasking the underlying autoimmune skin disease. |
| Databáze: | OpenAIRE |
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