EVALUATION OF FACTORS TO INFLUENCE TEOHPYLLINE CLEARANCE IN YOUNG CHILDREN WITH ACUTE ASTHMA

Autor:	Masafumi Zaitu, Waka Ito, Koichi Yamaguchi, Eisaku Iwasaki, Tokuko Mukoyama, Miki Morikawa, Minoru Baba, Yoko Miyabayashi, Kunio Ichikawa, Kan Toyama, Misa Watanabe, Kei Masuda
Rok vydání:	1995
Předmět:	Diarrhea business.industry Anesthesia Vomiting Medicine Theophylline Aminophylline medicine.symptom business Body weight medicine.disease medicine.drug Asthma
Zdroj:	Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology. 9:46-53
ISSN:	1882-2738 0914-2649
DOI:	10.3388/jspaci.9.46
Popis:	We evaluated the factors which influenced theophylline clearance during continuous intravenous aminophylline infusion in young athmatic children less than 2 years of age. We examined the relationship between the theophylline clearance and various factors sach as age, sex, body weight, fever, diarrhea and vomiting, in each of four deviled age groups.We analyzed these relationship using multi variant analysiswith the rate of discrimination of 84%.Low age (especialy under 6 months old), fever and diarrhea decreased theophylline clearance, but sex, body weight and vomiting were not related to theophylline clearance.These resalts suggest that the be age, diarrhea and fever should be considered when we start the continuous intravenous aminophylline infusion.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cf865ee493897b3431f7e6e9a820357e https://doi.org/10.3388/jspaci.9.46 Zobrazit plný text záznamu