Relations between myeloid and stromal cells of bone marrow in acute experimental aplasia

Autor:	N. A. Torubarova
Rok vydání:	1977
Předmět:	medicine.medical_specialty Pathology Stromal cell Myeloid General Medicine Aplasia Biology medicine.disease General Biochemistry Genetics and Molecular Biology Hypoplasia Haematopoiesis medicine.anatomical_structure Endocrinology Internal medicine medicine Femur Bone marrow Fibroblast
Zdroj:	Bulletin of Experimental Biology and Medicine. 83:225-229
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00799430
Popis:	Acute hypoplasia of the hematopoietic system was produced in guinea pigs by injecting vinblastin in a dose of 0.1 mg/100 g body weight intraperitoneally either once or twice at an interval of 7 days. The number of myelokaryocytes and the concentration (per 105 myelokaryocytes) and total number (per femur) of precursors of fibroblasts were determined in the femora by the fibroblast colony method. After injection of the cytostatic the decrease in number of myelokaryocytes was accompanied by a change in the concentration of stromal precursors per femur. It is postulated that the response of the bone marrow during hypoplasia is determined by interaction between the myeloid and stromal cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cf830a094d584e5bc3121cb9c7dc876d https://doi.org/10.1007/bf00799430 Zobrazit plný text záznamu Full text from SpringerLink