IMMUNOLOGICAL STUDIES ON PREGNANCY IN THE MOUSE

Autor: Ann G. Clarke
Rok vydání: 1984
Předmět:
DOI: 10.1016/b978-0-408-10865-2.50015-3
Popis: This chapter discusses immunological studies on pregnancy in the mouse. An understanding of the immune changes in pregnancy has gained from studies of inbred and congeneic strains of mice. The use of such animals has recently clarified the extent of the antigenicity of the mouse embryo, and they are now helping to unravel the details of responses to discrete antigenic differences between mother and fetus. Studies carried out sequentially through the whole course of pregnancy show that many of the maternal responses fluctuate greatly during gestation, and that quite large changes can occur over a very short period of time. There is also evidence that cellular and humoral immunity do not necessarily go hand in hand. The chapter also discusses nonimmunological factors that influence the immune responses in pregnancy.
Databáze: OpenAIRE